By MAJOR R. KAREN-BARBMAN, The New York Post, March 18, 2009
A recent study on the use of trimethoprim-sulfamethoxazole has shown that some people have no idea what is in the antibiotic. But that is the truth!
The study was published today in the New England Journal of Medicine.
The study, by researchers from Boston University, was published online today. The study examined the effects of sulfamethoxazole (brand name Bactrim), an antibiotic commonly prescribed for treating and preventing infections in both children and adults.
The researchers found that sulfamethoxazole was effective against both gram-positive and gram-negative bacteria and was associated with lower rates of antibiotic resistance than was the case.
But even when sulfamethoxazole was stopped, the rate of resistance was lower than was seen in people who took Bactrim alone.
There was a clear trend for the resistance rate to be lower than that seen in patients taking sulfamethoxazole, the researchers wrote in the paper. "Our data suggest that some people who use trimethoprim may be more susceptible to antibiotic resistance than others. Antibiotics prescribed for treating infections in patients with underlying conditions such as pneumonia, bronchitis, and sinusitis, or who are taking sulfamethoxazole or the combination of both, may be as effective as a drug for treating these conditions."
In a recent editorial in the journal, Dr. Michael P. Kaul, M. D., professor of medicine at Harvard Medical School, and lead author of the study, said that the findings should be considered in the context of the current evidence on the effectiveness of sulfamethoxazole for treating infections.
"In general, the evidence is mixed," said Dr. Kaul.
"The research on antibiotic resistance suggests that there is no reason for physicians to prescribe antibiotics for patients with underlying conditions such as pneumonia, bronchitis, and sinusitis. The research suggests that the use of antibiotics in pediatric patients is safe and effective in children, but that it is not a recommended or proven treatment for infections in children and adults."
The authors of the study cautioned that the research is based on a sample of more than 30,000 patients who had been diagnosed with respiratory infections and their risk of antibiotic resistance. Those who had been treated with sulfamethoxazole and sulfa drugs could be more susceptible to antibiotic resistance.
Sulfamethoxazole and sulfa drugs are not available over-the-counter, and they should be used only by those who are allergic to sulfa drugs. In the past, these drugs have been prescribed by doctors, but this is not new in New England.
A previous study in the journal reported that people who were taking sulfamethoxazole or sulfa drugs had higher rates of resistance to both penicillin and amoxicillin against gram-positive and gram-negative bacteria.
"If this study shows that trimethoprim-sulfamethoxazole is effective against gram-positive and gram-negative bacteria, we would expect to see a reduction in the rate of antibiotic resistance," said Dr. "The results of the study are preliminary, and we have not yet been able to establish that there is a significant relationship between the use of trimethoprim-sulfamethoxazole and antibiotic resistance."
This study was published online today in the New England Journal of Medicine.
Photo:A study of the effectiveness of trimethoprim-sulfamethoxazole (Bactrim) in treating infections in infants and children aged 4 to 11 years.
The researchers also found that patients who took sulfamethoxazole and sulfa drugs had higher rates of resistance to both penicillin and amoxicillin against gram-positive and gram-negative bacteria. The resistance rates were lower in people who were taking sulfamethoxazole than in those who were taking sulfa drugs.
The authors of the study were from the University of New England, Boston, who were part of a study of antibiotics in pediatric patients, including sulfamethoxazole and sulfa drugs. They had received training from doctors and researchers before the study. They were part of the Boston University School of Medicine's School of Pharmacy.
The Boston University study is called "The Effectiveness of Trimethoprim-Sulfamethoxazole on the Resistant Infections in Children and Adults," by the New England Journal of Medicine.
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StrimmedTogether™®Sulfamethoxazole (160mg) tabletsThis product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently-owned and operated pharmacy business. However, Strimmed Together may be used for other purposes, thus the product description for this medication does not require a prescription and can be read on-site for other products that do not require a prescription.
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This treatment plan reviews the risks and benefits of the treatment we are recommending. Please make sure to read it and the manufacturer's pamphlet that comes with the medicine. The manufacturer's pamphlet contains the full information on interactions, side effects, and other important information you should know about the medicine before you start.
You have stated that you wish to take a medication for your symptoms of bacterial vaginitis/vaginosis.Bactrimis what’s needed to maintain an erection during sex and can be taken with or without food. Bactrim passes into your breast milk, and if you are a nursing mother, you can message the company thatcraftedilium.com by joining theottonmouth.net blog. You will need to see the side effects and manage them for the full year after you Availability Bactrim comes in the following strengths:
The contents of the manufacturer's pamphlet, which is assembled by AstraZeneca Pharmaceuticals, contains the full information on interactions, side effects, and other important information you should know before you start taking Bactrim. If you are a nursing mother who is seeking guidance on managing side effects, you'll need to see the benefits and importance of including the information in the catalog.
Bactrim is not recommended for use in infants less than 12 months of age in those with liver or kidney problems or who are breastfeeding. It is not intended for use in women.Call your doctor immediately if you notice the appearance of serious condition, including liver problems, kidney problems, or kidney failure in the next sexual intercourse.
If you are taking cyclosporine, leflunomide, or ertapenem for bacterial vaginosis, your doctor will tell you how to take Bactrim.Take Bactrim with food or milk. Avoid grapefruit juice, alcohol, or marijuana during your treatment with Bactrim. The combination can cause unwanted side effects. If you have trouble getting or maintaining an erection, get medical help right away with Bactrim.
You must tell the doctor about all your other medical conditions. Some conditions can require you to take Bactrim with food or milk. For example, if you are taking leflunomide for bacterial vaginosis, your doctor will tell you how to take Bactrim. If you are taking azithromycin for bacterial vaginosis, your doctor will tell you how to take Bactrim.
You must tell the doctor about any vaccinations you take. For example, if you are being taken by people who have longatility data, don’t take the drug. If you are being taken by people who take marijuana during therapy, don’t take the drug.
If you take Bactrim with blood thinners, you may be given a low-dose of blood thinner, such as warfarin, to keep the thrombophilic bacteria from multiplying and spreading. Ask your doctor how to take Bactrim if you are not sure.
Some medicines can interfere with each other. Do not stop using any other medicines without first consulting your doctor.
If you experience any serious side effects, you can call your doctor. The side effects you may experience may be:
This is not a complete list of side effects. If you notice other side effects not listed above, contact your doctor or pharmacist available in your local area. You can also call a poison control line at 1-800-222-1222 to talk to a healthcare provider. You can also use a local medication online program that can help you identify ED symptoms.
You should not use Bactrim if you have any of the following:
You should NOT take Bactrim if you are pregnant or breastfeeding without consulting your doctor. Bactrim can cause harm to the fetus or baby.
It’s super easy to use. Simply take one tablet at a time with the instructions given by the healthcare provider in the patient information leaflet.
1 tablet Bactrim
2 tablets Bactrim
10-30 minutes of using it will help
Do not take it with other ingredients to prevent your body from taking all of the steps to treat.
Takejoice�it works fasterif you take itfaster– take it as prescribed by your doctor
works– take it as prescribed by the doctor
Some side effects may pass before you see any positive in themselves.
Some other side effects have been reported, but not when taking this medicine.
You can also ask the doctor if you have kidney problems or liver problems.
Talk with the doctor if you have any other health problems,,, or a history of,,,,, or yeast infections in your family.
Your doctor will talk with you through a plan to lessen your symptoms and prevent future episodes of yeast infections.
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